What Is Nembutal Injectable Used For?
Nembutal sodium injection Solution (pentobarbital sodium injection) is a sterile solution for intravenous or intramuscular injection. Each mL contains pentobarbital sodium 50 mg, in a vehicle of propylene glycol, 40%, alcohol, 10% and water for injection, to volume. The pH is adjusted to approximately 9.5 with hydrochloric acid and/or sodium hydroxide.
NEMBUTAL Sodium is a short-acting barbiturate, chemically designated as sodium 5-ethyl-5-(1-methylbutyl) barbiturate. The structural formula for pentobarbital sodium is. Nembutal Sodium is used short-term as a sedative to treat insomnia, or to cause you to fall asleep for surgery. This medicine is also used as an emergency treatment for seizures.
Nembutal Sodium may also be used for purposes not listed in this medication guide.
Before taking this Nembutal sodium injection
- a history of porphyria (a genetic enzyme disorder that causes symptoms affecting the skin or nervous system).
To make sure Nembutal Sodium is safe for you, tell your doctor if you have:
- liver disease;
- kidney disease;
- temporary or chronic pain;
- a history of addiction to phenobarbital or similar medicines (Valium, Xanax, Ativan, and others).
Using Nembutal Sodium during pregnancy could harm the unborn baby. If you use this medicine while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant.
How is Nembutal sodium injection given?
Follow all directions on your prescription label. Do not use Nembutal Sodium in larger or smaller amounts or for longer than recommended.
Nembutal Sodium may be habit-forming. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law.
Nembutal Sodium is injected into a muscle, or into a vein through an IV. A healthcare provider will usually give you this injection.
You may be shown how to use Nembutal Sodium at home. Do not give yourself this medicine if you do not understand how to use the injection and properly dispose of needles, IV tubing, and other items used.
Since Nembutal Sodium is often used only when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
Seek emergency medical attention if you think you have used too much of Nembutal Sodium. An overdose of pentobarbital can be fatal.
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- confusion, agitation, hallucinations;
- weak or shallow breathing;
- slow heart rate, weak pulse; or
- a light-headed feeling, like you might pass out.
Side effects such as confusion, depression, or excitement may be more likely in older adults and those who are ill or debilitated.
Common side effects may include:
- drowsiness, dizziness;
- loss of balance or coordination;
- nausea, vomiting, constipation;
- overactive reflexes;
- sleep problems (insomnia), nightmares; or
- feeling restless or excited (especially in children or older adults).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Using Nembutal Sodium with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before taking a sleeping pill, narcotic pain medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression, or seizures.
Tell your doctor about all other medications you use, especially:
- birth control pills or hormone replacement estrogens;
- a blood thinner–warfarin, Coumadin, Jantoven;
- an MAO inhibitor—isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others;
- other seizure medications–divalproex, phenytoin, valproic acid (Depakene); or
- steroid medicine–prednisone, dexamethasone, prednisolone, and others.
This list is not complete. Other drugs may interact with pentobarbital, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.