1 Syringe x 2ml per pack



Designed to treat osteoarthritis knee joint pain by restoring the combined elasticity and viscosity within the joint.

Hylane G-F 20 is available in two forms:

Synvisc, 2 ml: 2.25 ml glass syringe (cans of 1 [ACL 3401078489921] and 3 [ACL 3401076479283]).

Synvisc-One, 6 ml: 10 ml glass syringe (ACL 3401048640222).

Hylan G-F is a sterile, pyrogen-free, viscoelastic liquid containing the hylan A and hylan B polymers produced from a highly purified bird extract. Hylans are derivatives of hyaluronan (sodium hyaluronate), and they are composed of recurrent disaccharide units of N-acetylglucosamine and sodium glucuronate.

Hylan A has an average molecular weight of 6,000,000 daltons and hylan B is a hydrated gel. Hylan G-F contains hylan A and hylan B (8.0 mg ± 2.0 mg / ml) in a physiological saline solution of buffered sodium chloride (pH 7.2 ± 0.3).

For 1 ml (Hylan G-F 20): hylan 8.0 mg, sodium chloride 8.5 mg, disodium phosphate 0.16 mg, sodium dihydrogen phosphate 0.04 mg, water for injections qs.

Synvisc contains 2 ml of Hylan G-F 20. Synvisc-One contains 6 ml of Hylan G-F 20.

Hylan G-F is biologically similar to hyaluronan. Hyaluronan is a component of the synovial fluid that gives it its viscoelasticity. The mechanical (viscoelastic) properties of Hylane G-F, however, are superior to those of synovial fluid and hyaluronan solutions of similar concentrations. Hylane GF 20 has an elasticity (storage coefficient G ‘) at 2.5 Hz of 111 ± 13 pascals (Pa) and a viscosity (loss coefficient G’ ‘) of 25 ± 2 Pa. The elasticity and the viscosity of the synovial fluid of the knee of subjects aged 18 to 27 years measured with a method comparable to 2.5 Hz are G ‘= 117 ± 13 Pa; G ” = 45 ± 8 Pa. Hylans are metabolized in the body by the same route as hyaluronan and the products of their degradation are not toxic.


There are no reviews yet.

Be the first to review “SYNVISC 2ML”

Your email address will not be published. Required fields are marked *

Shopping Cart
Open chat